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Sino Biological
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Vetoquinol sa
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ADInstruments
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R&D Systems
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Image Search Results
Journal: Cancer Immunology, Immunotherapy : CII
Article Title: COM902, a novel therapeutic antibody targeting TIGIT augments anti-tumor T cell function in combination with PVRIG or PD-1 pathway blockade
doi: 10.1007/s00262-021-02921-8
Figure Lengend Snippet: COM902 does not induce ADCC or CDC activity. a ADCC activity assessment for COM902. b CDC activity assessment for COM902. Campath (anti-CD52) hIgG1 was used as a positive control. Representative data from n ≥ 2 is shown for each graph
Article Snippet: For blocking experiments, the cell lines described above were pre-incubated with COM902 or hIgG4 isotype for 30 min. Recombinant hPVR-mIgG2a-Fc (hPVR-Fc) and cynomolgus PVR-hIgG1-Fc-biotin (cPVR-Fc) produced internally, or
Techniques: Activity Assay, Positive Control